The Gut- Brain Connection
The gut-brain axis is actually quite fascinating in its complex interplay among several systems within the body, which communicate bidirectionally from the gut to the brain, thereby influencing mood, cognition, and even behavior—that is how integrated physical and mental health could be. We delve deep in this chapter into the underlying mechanisms, key players, and implications of this connection. 1. Gut-Brain Axis: A Communication Network The gut-brain axis has been defined as the major system allowing exchange of information between the gut and the brain. It reflects cross-talks between the CNS and ENS, this latter sometimes said to be the "second brain" because it autonomously governs gut functions. Sometimes, these two systems communicate with a mix of nerves, hormones, immune pathways, and neurotransmitters: Vagus Nerve : This is the longest cranial nerve directly connecting the brain stem to the digestive tract. It is considered to play a major role in the transmission ...